![]() If there are local symptoms to the eyes or respiratory tract, atropine is not indicated. Atropine is only useful to counter muscarinic effects (pralidoxime and benzodiazepines act on the others). It is not formally recommended for routine use in controlled airways, though it can be used off-label for minimizing secretions in the intubated patient.Īcetylcholine works on three different receptors that merit attention in nerve agent poisonings. While atropine can be used independently for anti-salivation effects, it most commonly is secondary to anticholinergic or antimuscarinic poisoning, as discussed below. ![]() It was originally synthesized from the plant Atropa belladonna which is where the drug derives its name. Review interprofessional team strategies for improving care coordination and communication to enhance patient outcomes and minimize adverse events with atropine.Ītropine or atropine sulfate carries FDA indications for anti-sialagogue/anti-vagal effect, organophosphate/muscarinic poisoning, and bradycardia.Summarize the indications for atropine use.Describe the potential adverse effects of atropine.Identify the mechanism of action of atropine.This activity outlines the indications, mechanism of action, safe administration, adverse effects, contraindications, toxicology, and monitoring of atropine. Atropine acts as a competitive, reversible antagonist of muscarinic receptors: an anticholinergic drug. ![]() Atropine or atropine sulfate carries FDA indications for anti-sialagogue/anti-vagal effect, organophosphate/muscarinic poisoning, and bradycardia. ![]()
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